Japanese quail Coturnix coturnix japonica reach sexual maturity earlier, breed rapidly and successfully, and cost less and require less space than other birds raised commercially. Given the value of this species for food production and experimental use, more studies are necessary to determine chromosomal regions and genes associated with gender and breed-differentiation. This study employed Trinity and edgeR for transcriptome analysis of next-generation RNA-seq data, which included 4 tissues obtained from 3 different breeding lines of Japanese quail random bred control, heavy weight, low weight. Differentially expressed genes shared between female and male tissue contrast groups were analyzed to identify genes related to sexual dimorphism as well as potential novel candidate genes for molecular sexing. Male Brain and Ovary vs. Testis indicates that these genes may regulate sex-specific anatomical development.
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Gene expression - Wikipedia
Startseite Graduate Thesis Or Dissertation. Sie haben keinen Zugang zu vorhandenen Sammlungen. Histone deacetylase inhibitors HDACIs are known to alter gene expression by both up- and down-regulation of protein coding genes in normal and cancer cells. However, the mechanisms that are responsible for activation and repression of gene expression remain obscure.
The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose or lac operon.